Description

Methyl 3-Bromo-2-Iodobenzoate is a high-purity, multi-halogenated aromatic ester building block of significant importance in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the selective introduction of both bromine and iodine functionalities into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring selective halogenation for bioactivity or further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the halogenated benzoate core is integral to the molecule's function.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials with tailored properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the orthogonal reactivity of the bromine and iodine atoms.
• Ligand and Catalyst Development: Employed in the preparation of complex organic ligands and catalysts used in asymmetric synthesis and catalysis.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems, leveraging the halogens for further bioconjugation.

Basic Information

Item	Detail
Product Name	Methyl 3-Bromo-2-Iodobenzoate
CAS No.	121772-84-7
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	3-Bromo-2-iodobenzoic Acid Methyl Ester; Methyl 3-Bromo-2-iodobenzoate; Benzoic acid, 3-bromo-2-iodo-, methyl ester; Methyl ester of 3-bromo-2-iodobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-2-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.