Description

4-Methyl-1H-Pyrazole-1-Carboxylic Acid 1,1-Dimethylethyl Ester is a high-purity, protected pyrazole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrazole or fused pyrazole ring systems.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Intermediate in the production of modern pesticides, herbicides, and fungicides that utilize heterocyclic chemistry.
• Chemical Biology Probes: Serves as a precursor for the development of molecular probes and tool compounds used in biochemical and cellular assays.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Academic Research: Used in university and institutional laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Methyl-1H-Pyrazole-1-Carboxylic Acid 1,1-Dimethylethyl Ester
CAS No.	121669-69-0
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	tert-Butyl 4-Methyl-1H-pyrazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-methyl-1H-pyrazole; 4-Methyl-1H-pyrazole-1-carboxylic acid tert-butyl ester; Boc-4-Methylpyrazole; 1-Boc-4-Methylpyrazole; 4-Methylpyrazole-1-carboxylic Acid tert-Butyl Ester; tert-Butyl 4-Methylpyrazole-1-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Methyl-1H-Pyrazole-1-Carboxylic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.