Description

4'-Amino-4-(Methylthio)Chalcone is a functionalized chalcone derivative characterized by its amino and methylthio substituents, which impart unique chemical reactivity and biological activity. This compound serves as a versatile and valuable pharmaceutical intermediate and organic building block for synthesizing more complex heterocyclic systems. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of new active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Agrochemical Research: Used as a lead compound or intermediate for developing new pesticides and herbicides with enhanced efficacy.
• Organic Synthesis Building Block: Employed in cyclization reactions to create privileged scaffolds like pyrazolines, flavones, and other nitrogen/ sulfur-containing heterocycles.
• Material Science: Investigated for its potential in creating organic semiconductors, nonlinear optical materials, or metal-organic frameworks (MOFs).
• Biochemical Research: Serves as a tool compound in biochemical assays to study enzyme inhibition or protein-ligand interactions.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments due to its conjugated system and functional groups.

Basic Information

Product Name	4'-Amino-4-(Methylthio)Chalcone
CAS No.	121645-99-6
Molecular Formula	C₁₇H₁₇NOS
Molecular Weight	283.39 g/mol
Synonyms	1-(4-Aminophenyl)-3-[4-(methylthio)phenyl]-2-propen-1-one; 4'-Amino-4-methylmercaptochalcone; (E)-1-(4-Aminophenyl)-3-(4-(methylthio)phenyl)prop-2-en-1-one; 4-Amino-4'-(methylthio)chalcone; 4'-Amino-4-(methylsulfanyl)chalcone; 4-Methylthio-4'-aminochalcone; AMTC; NSC 405122
EINECS	Contact for details

Quality Control

Our 4'-Amino-4-(Methylthio)Chalcone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment ensures the material meets the high standards required for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.