Description

(2R)-Benzylamino-Phenyl-Acetic Acid Methyl Ester is a chiral, non-natural amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is essential for achieving desired biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), peptide mimetics, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptidomimetics Synthesis: Used to incorporate unnatural amino acid residues into peptide chains to enhance metabolic stability and bioavailability.
• Asymmetric Catalysis: Serves as a precursor or ligand in the preparation of chiral catalysts for enantioselective synthesis.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and protein-protein interactions through the creation of tailored molecular probes.
• Agrochemical Development: Potential intermediate in the synthesis of chiral active ingredients for crop protection products.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process development.

Basic Information

Product Name	(2R)-Benzylamino-Phenyl-Acetic Acid Methyl Ester
CAS No.	121440-91-3
Molecular Formula	C₁₆H₁₇NO₂
Molecular Weight	255.31 g/mol
Synonyms	Methyl (2R)-2-(benzylamino)-2-phenylacetate; (R)-Methyl 2-(benzylamino)-2-phenylacetate; D-Benzylamino-phenylacetic acid methyl ester; (R)-Benzylamino-phenyl-acetic acid methyl ester; (αR)-α-(Benzylamino)benzenacetic acid methyl ester; Methyl (R)-2-(benzylamino)-2-phenylacetate; (R)-2-(Benzylamino)-2-phenylacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our (2R)-Benzylamino-Phenyl-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (e.e.)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.