Description

5-[2-Chloro-5-(Trifluoromethyl)Phenoxy]-2-Nitrobenzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a distinct trifluoromethylphenoxy-nitrobenzoate structure. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in agrochemical and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for developing novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, especially in therapeutic areas requiring trifluoromethylated motifs.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and pesticides, leveraging its phenoxy and nitro functional groups.
• Chemical Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or liquid crystals due to its aromatic and ester functionalities.

Basic Information

Product Name	5-[2-Chloro-5-(Trifluoromethyl)Phenoxy]-2-Nitrobenzoic Acid Methyl Ester
CAS No.	121325-44-8
Molecular Formula	C15H9ClF3NO5
Molecular Weight	375.68 g/mol
Synonyms	Methyl 5-[2-chloro-5-(trifluoromethyl)phenoxy]-2-nitrobenzoate; 2-Nitro-5-[2-chloro-α,α,α-trifluoro-p-tolyloxy]benzoic Acid Methyl Ester; Benzoic acid, 5-[2-chloro-5-(trifluoromethyl)phenoxy]-2-nitro-, methyl ester; Methyl 2-nitro-5-[2-chloro-5-(trifluoromethyl)phenoxy]benzoate
EINECS	Contact for details

Quality Control

Our production of 5-[2-Chloro-5-(Trifluoromethyl)Phenoxy]-2-Nitrobenzoic Acid Methyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) are provided with each shipment, detailing specifications such as assay, identity, and impurity profiles. We operate under a cGMP-compliant quality management system, and our facilities are prepared to meet the audit requirements of global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.