Description

Benzenepropanoic Acid, α-[(Acetyloxy)Methyl]-, (αs)- is a specialized chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which make it a critical building block for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Peptidomimetics & Prodrug Development: Serves as a building block for designing peptide analogs and prodrug formulations to enhance bioavailability and metabolic stability.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies in organic chemistry and the exploration of new synthetic pathways.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for various advanced material applications.

Basic Information

Product Name	Benzenepropanoic Acid, α-[(Acetyloxy)Methyl]-, (αs)-
CAS No.	121232-85-7
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(αS)-α-[(Acetyloxy)methyl]benzenepropanoic acid; (S)-3-Phenyl-2-(acetoxymethyl)propionic acid; (S)-2-(Acetoxymethyl)-3-phenylpropanoic acid; (S)-α-(Acetoxymethyl)benzenepropanoic acid; (S)-3-Phenyl-2-(acetoxymethyl)propanoic acid; (S)-2-(Hydroxymethyl)-3-phenylpropionic acid acetate; A chiral phenylpropanoic acid derivative
EINECS	Contact for details

Quality Control

Our Benzenepropanoic Acid, α-[(Acetyloxy)Methyl]-, (αs)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and identification. We support compliance with cGMP guidelines for pharmaceutical intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.