Description

4,6-Ethylidene Glucose Streptozotocin is a chemically modified derivative of the antibiotic and antineoplastic agent streptozotocin. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a targeted prodrug or a tool compound in metabolic studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology research, diabetes studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Research: Serves as a key intermediate or precursor in the synthesis of novel streptozotocin analogs for anticancer and diabetogenic studies.
• Oncology Studies: Used as a research chemical to investigate mechanisms of selective toxicity in pancreatic beta cells and certain cancer cell lines.
• Biochemical Tool: Employed in metabolic pathway research to study glucose transport and DNA alkylation processes.
• Prodrug Development: Investigated for the design of glucose-conjugated prodrugs aiming for targeted drug delivery systems.
• Academic Research: Utilized in university and institutional labs for chemical biology and medicinal chemistry projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4,6-Ethylidene Glucose Streptozotocin
CAS No.	121230-21-5
Molecular Formula	C14H22N4O8
Molecular Weight	374.35 g/mol
Synonyms	Streptozocin 4,6-Ethylidene Glucose Derivative; 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-α-D-glucopyranose, 4,6-O-ethylidene-; 4,6-O-Ethylidene-N-(methylnitrosocarbamoyl)-α-D-glucosamine; N-(Methylnitrosocarbamoyl)-4,6-O-ethylidene-α-D-glucosamine; STZ 4,6-Ethylidene Derivative; NSC 85998 (4,6-Ethylidene analog); Streptozotocin 4,6-acetal
EINECS	Contact for details

Quality Control

Our 4,6-Ethylidene Glucose Streptozotocin is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use and stored under recommended conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.