Description

(±)-Dihydroguaiaretic Acid is a synthetic, racemic form of the naturally occurring lignan, dihydroguaiaretic acid. This compound is valued as a versatile chemical intermediate and research standard for its structural and biological properties. It is primarily utilized by pharmaceutical, nutraceutical, and fine chemical research and development sectors for synthesis, analytical reference, and biological studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard in studies investigating antioxidant, anti-inflammatory, and enzyme-inhibitory activities.
• Nutraceutical Development: Employed in research for formulating dietary supplements targeting oxidative stress.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex lignan derivatives and specialty chemicals.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, GC, LC-MS).

Basic Information

Product Name	(±)-Dihydroguaiaretic Acid
CAS No.	121209-88-9
Molecular Formula	C20H26O4
Molecular Weight	330.42 g/mol
Synonyms	meso-Dihydroguaiaretic Acid; (±)-Dihydroguaiaretic Acid; NSC 122044; 2,5-Bis(3,4-dimethoxyphenyl)tetrahydrofuran; DL-Dihydroguaiaretic Acid; 4,4'-(2R,3S,4S,5R)-Tetrahydro-3,4-dimethyl-2,5-furandiyl)bis(1,2-dimethoxybenzene); (±)-2,3-Bis(3,4-dimethoxyphenyl)butane-1,4-diol (cyclic ether form)
EINECS	Contact for details

Quality Control

Our (±)-Dihydroguaiaretic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.