Description

(E)-Diethyl 4-Hydroxybut-2-Enylphosphonate is a high-purity organophosphorus compound characterized by its unique phosphonate ester and hydroxyl-functionalized alkene structure. This versatile chemical intermediate is valued for its role in advanced organic synthesis, particularly in the construction of complex molecules through carbon-carbon and carbon-phosphorus bond-forming reactions. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized phosphonate-based ligands for metal catalysis.
• Material Science: Employed in the development of flame retardants, polymer modifiers, and specialty surfactants.
• Organic Synthesis Reagent: Facilitates Horner-Wadsworth-Emmons (HWE) olefination reactions to form (E)-configured alkenes with high stereoselectivity.
• Academic & Industrial R&D: A critical reagent for methodological development and exploring new reaction pathways in synthetic chemistry.

Basic Information

Product Name	(E)-Diethyl 4-Hydroxybut-2-Enylphosphonate
CAS No.	121077-61-0
Molecular Formula	C8H17O4P
Molecular Weight	208.19 g/mol
Synonyms	Diethyl (E)-4-Hydroxy-2-butenylphosphonate; (E)-4-Hydroxy-2-butenylphosphonic Acid Diethyl Ester; (E)-Diethyl (4-Hydroxybut-2-en-1-yl)phosphonate; 2-Buten-1-ol, 4-hydroxy-, diethyl phosphate, (E)-; Diethyl (E)-4-hydroxybut-2-enylphosphonate; Phosphonic acid, P-[(1E)-4-hydroxy-2-buten-1-yl]-, diethyl ester
EINECS	Contact for details

Quality Control

Our (E)-Diethyl 4-Hydroxybut-2-Enylphosphonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
(E)-Isomer Content (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.