Description

o-Phosphoserine-p-Ethyl Ester CAS NO 121071-26-9 is a chemically modified derivative of the amino acid serine, specifically phosphorylated at the hydroxyl group and esterified with ethanol. This compound is a critical building block and synthetic intermediate in advanced organic and medicinal chemistry. It is primarily utilized by pharmaceutical researchers, peptide chemists, and agrochemical developers for the synthesis of complex molecules, including peptide mimetics and prodrugs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of phosphopeptide analogs and prodrugs for targeted drug delivery.
• Peptide Chemistry Research: Used to incorporate phosphorylated serine residues into synthetic peptides for studying protein phosphorylation and signal transduction pathways.
• Biochemical Probe Development: Serves as a substrate or inhibitor in enzymatic assays for kinases and phosphatases.
• Agrochemical Synthesis: Intermediate in the development of novel, bioactive compounds for crop protection.
• Chemical Biology Tool: Employed in the study of post-translational modifications and the development of activity-based probes.
• Academic & Industrial R&D: Fundamental building block for exploratory research in medicinal chemistry and chemical biology.

Basic Information

Product Name	o-Phosphoserine-p-Ethyl Ester
CAS No.	121071-26-9
Molecular Formula	C5H12NO6P
Molecular Weight	213.12 g/mol
Synonyms	O-Phospho-L-serine ethyl ester; L-Serine, O-phosphono-, ethyl ester; Phosphoserine ethyl ester; (2S)-2-Amino-3-(phosphonooxy)propanoic acid ethyl ester; Serine phosphate ethyl ester; H-Ser(PO3H2)-OEt; Fmoc-Ser(PO(OBzl)OH)-OH related intermediate; Ethyl (2S)-2-amino-3-(phosphonooxy)propanoate
EINECS	Contact for details

Quality Control

Our o-Phosphoserine-p-Ethyl Ester is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in research and development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the container to reach ambient temperature before opening to minimize moisture condensation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.