Description

Carbamic Acid, (1-Methyl-2-Oxo-3-Butenyl)-, 1,1-Dimethylethyl Ester, (R)- (9Ci) is a high-purity, chiral building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the production of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing stereochemically defined molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used in the construction of complex natural products and novel chemical entities where the (R)- stereochemistry is essential for biological activity.
• Peptidomimetic Research: Serves as a building block for developing peptide analogs and protease inhibitors in medicinal chemistry programs.
• Agrochemical Development: Employed in the research and synthesis of new, enantiomerically pure herbicides and fungicides.
• Catalyst Ligand Precursor: Can be utilized in the development of novel chiral ligands for asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and drug discovery pathways.

Basic Information

Product Name	Carbamic Acid, (1-Methyl-2-Oxo-3-Butenyl)-, 1,1-Dimethylethyl Ester, (R)- (9Ci)
CAS No.	120881-97-2
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(R)-tert-Butyl 1-methyl-2-oxo-3-butenylcarbamate; (R)-N-Boc-3-Buten-2-one; (R)-1-Boc-amino-1-buten-3-one; (R)-N-(tert-Butoxycarbonyl)-3-buten-2-imine; tert-Butyl (R)-(1-methyl-2-oxo-3-butenyl)carbamate; (R)-Boc-Protected Butenone; (3R)-3-[(tert-Butoxycarbonyl)amino]but-3-en-2-one
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (1-Methyl-2-Oxo-3-Butenyl)-, 1,1-Dimethylethyl Ester, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.