Description

Threo-Pentaric Acid, 3-Deoxy-, 1,4-Lactone (9Ci) is a specialized chiral lactone derivative of pentaric acid. This compound serves as a valuable synthetic intermediate and building block in advanced organic synthesis, particularly for the construction of complex carbohydrate analogs and nucleoside derivatives. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, process development, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of nucleoside analogs and antiviral/antitumor drug candidates.
• Carbohydrate Chemistry Research: Used as a building block for the preparation of deoxy-sugar derivatives and complex oligosaccharide mimics.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the development of glycosidase inhibitors.
• Process Chemistry: Serves as a starting material for scale-up synthesis and route development in active pharmaceutical ingredient (API) manufacturing.
• Biochemical Research: Potential use in studying enzyme mechanisms related to carbohydrate metabolism.
• Fine Chemical Synthesis: A versatile intermediate for creating specialty chemicals with specific stereochemistry.

Basic Information

Product Name	Threo-Pentaric Acid, 3-Deoxy-, 1,4-Lactone (9Ci)
CAS No.	120742-25-8
Molecular Formula	C5H8O5
Molecular Weight	148.11 g/mol
Synonyms	3-Deoxy-threo-pentaric acid 1,4-lactone; 3-Deoxy-DL-threo-pentono-1,4-lactone; 3-Deoxypentaric acid 1,4-lactone; 1,4-Lactone of 3-deoxy-threo-pentaric acid; (3R,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one (racemic); DL-3-Deoxypentono-1,4-lactone; Threo-3-deoxypentono-1,4-lactone
EINECS	Contact for details

Quality Control

Our Threo-Pentaric Acid, 3-Deoxy-, 1,4-Lactone (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, strength, and purity. Certificates of Analysis (COA) detailing all test results are provided and available upon request. We support cGMP standards for pharmaceutical applications and can accommodate custom purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (as threo isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.