Description

Methyl 3-(tert-Butyldimethylsilyloxy)Benzoate CAS NO 120687-94-7 is a high-purity, protected phenolic ester derivative, serving as a versatile and critical synthetic intermediate in advanced organic chemistry. Its primary value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which provides exceptional stability under a wide range of reaction conditions, enabling precise multi-step synthesis. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors who require reliable building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted benzoate or phenol motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the protected hydroxyl group is crucial for selective reactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Chemistry: Employed in the creation of specialty monomers and polymers with tailored thermal and chemical properties.
• Peptide & Natural Product Synthesis: Facilitates the introduction of aromatic carboxylic acid derivatives into complex molecules while protecting sensitive functional groups.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Item	Detail
Product Name	Methyl 3-(tert-Butyldimethylsilyloxy)Benzoate
CAS No.	120687-94-7
Molecular Formula	C14H22O3Si
Molecular Weight	266.41 g/mol
Synonyms	Methyl 3-[(1,1-Dimethylethyl)dimethylsilyl]oxy]benzoate; 3-[(tert-Butyldimethylsilyl)oxy]methyl benzoate; Methyl 3-(TBDMS-oxy)benzoate; Benzoic acid, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester; 3-(tert-Butyldimethylsiloxy)benzoic acid methyl ester; Methyl m-(tert-butyldimethylsilyloxy)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(tert-Butyldimethylsilyloxy)Benzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Every lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.