Description

Rac All-Trans 3-Hydroxy Retinoic Acid Ethyl Ester is a synthetic derivative of retinoic acid, a key molecule in cellular signaling and differentiation. This compound is valued for its role as a versatile biochemical tool and a critical intermediate in the synthesis of more complex retinoids and pharmaceutical actives. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel retinoid-based drugs targeting dermatological conditions, oncology, and metabolic diseases.
• Biochemical Research: Used as a reference standard or experimental compound in studies of retinoid metabolism, nuclear receptor (RAR/RXR) signaling pathways, and cellular differentiation.
• Cosmeceutical R&D: Serves as a precursor or model compound for developing new active ingredients in anti-aging and skin-rejuvenation formulations.
• Chemical Synthesis: An important chiral synthon for organic chemists creating libraries of retinoid analogs with modified biological activity.
• Analytical Standard: Employed in HPLC, LC-MS, or GC-MS methods for the qualitative and quantitative analysis of retinoids in various matrices.

Basic Information

Product Name	Rac All-Trans 3-Hydroxy Retinoic Acid Ethyl Ester
CAS No.	120674-74-0
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	Ethyl 3-Hydroxyretinoate; all-trans-3-Hydroxyretinoic Acid Ethyl Ester; 3-Hydroxyretinoic Acid Ethyl Ester; Retinoic Acid, 3-Hydroxy-, Ethyl Ester; Vitamin A Acid, 3-Hydroxy-, Ethyl Ester; Ethyl (2E,4E,6E,8E)-3-hydroxy-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate
EINECS	Contact for details

Quality Control

Our Rac All-Trans 3-Hydroxy Retinoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C (refrigerated) or -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.