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Bis(Epideoxydihydroqinghaosu) Ether CAS NO 120224-11-5


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CAS No.:120224-11-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis(Epideoxydihydroqinghaosu) Ether is a synthetic derivative of artemisinin, a key sesquiterpene lactone known for its potent biological activity. This compound is valued for its role as a crucial intermediate in advanced pharmaceutical research and synthesis, particularly in the development of next-generation antimalarial and antiparasitic agents. It serves the needs of research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on innovative therapeutic solutions.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of novel artemisinin-based antimalarial drugs and combination therapies (ACTs).
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with enhanced efficacy and reduced resistance.
  • Antiparasitic Agent Development: Investigated for potential applications against other parasitic diseases beyond malaria.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
  • Biochemical Research: Employed in studies exploring the mechanism of action of sesquiterpene lactones and their interaction with biological targets.
  • Fine Chemical Synthesis: Utilized as a specialized intermediate for creating complex, high-value molecules in contract research and manufacturing.

Basic Information

Product Name Bis(Epideoxydihydroqinghaosu) Ether
CAS No. 120224-11-5
Molecular Formula C30H44O8
Molecular Weight 532.67 g/mol
Synonyms Bis(epideoxydihydroartemisinin) Ether; Dihydroartemisinin Ether Dimer; Arteether Analog; Artemisinin Dimer Ether; 1,2,4,5-Tetraoxane Derivative; [3R-(3α,5aβ,6β,8aβ,9R*,10R*,12aβ,12bα)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol, Dimer
EINECS Contact for details

Quality Control

Our Bis(Epideoxydihydroqinghaosu) Ether is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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