Description

Methyl 4-((tert-Butoxycarbonylamino)Methyl)Benzoate is a high-purity, protected amino acid derivative and a crucial pharmaceutical intermediate. Its primary value lies in its role as a versatile building block for the synthesis of complex molecules, particularly in peptide chemistry and drug discovery. This compound is essential for research and development laboratories, as well as production facilities in the pharmaceutical and biotechnology sectors, where it is used to introduce the Boc-protected aminomethylbenzoic acid moiety into target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing modified phenylalanine or tyrosine analogs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a protected aminomethylbenzoic acid residue, enabling the creation of novel peptide sequences with enhanced stability or biological activity.
• Protease Inhibitor Development: Serves as a core scaffold or intermediate in the research and production of protease inhibitors, which are important for treating various diseases.
• Linker Chemistry: Utilized in the construction of chemical linkers for bioconjugation, drug delivery systems, and the development of antibody-drug conjugates (ADCs).
• Organic Synthesis Reagent: Employed in academic and industrial organic chemistry research for the preparation of complex organic molecules, including heterocycles and functionalized aromatics.
• Chemical Biology Probes: Acts as a precursor for synthesizing labeled compounds and probes used to study biological processes and enzyme functions.

Basic Information

Product Name	Methyl 4-((tert-Butoxycarbonylamino)Methyl)Benzoate
CAS No.	120157-96-2
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	Methyl 4-[[(tert-Butoxycarbonyl)amino]methyl]benzoate; 4-((Boc-amino)methyl)benzoic acid methyl ester; Methyl p-((tert-Butoxycarbonylamino)methyl)benzoate; Methyl 4-[(tert-Butoxycarbonylamino)methyl]benzoate; Boc-NH-CH2-C6H4-COOCH3; (4-(Methoxycarbonyl)phenyl)methyl tert-butylcarbamate; Benzoic acid, 4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-((tert-Butoxycarbonylamino)Methyl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring a reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.