Description

Methyl 4,6-Dibromo-3-Fluoro-2-Methylbenzoate is a high-purity, multi-halogenated aromatic ester building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the halogen pattern can influence bioavailability and environmental stability.
• Material Science: Acts as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with unique optical or electronic characteristics.
• Chemical Biology: Employed as a probe or labeling reagent due to the reactivity of the halogen atoms for cross-coupling reactions in bioconjugation strategies.
• Organic Synthesis: A versatile building block for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex, poly-substituted aromatic systems.

Basic Information

Product Name	Methyl 4,6-Dibromo-3-Fluoro-2-Methylbenzoate
CAS No.	119916-08-4
Molecular Formula	C9H7Br2FO2
Molecular Weight	325.96 g/mol
Synonyms	Methyl 2,4-dibromo-5-fluoro-6-methylbenzoate; 4,6-Dibromo-3-fluoro-2-methylbenzoic acid methyl ester; Benzoic acid, 4,6-dibromo-3-fluoro-2-methyl-, methyl ester; 2-Methyl-4,6-dibromo-3-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 4,6-Dibromo-3-Fluoro-2-Methylbenzoate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established analytical methods, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.