Description

(R)-(+)-2-Benzylsuccinic Acid 1-Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and functional group arrangement, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and other optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Used as a starting material or intermediate in stereoselective reactions to introduce the (R)-configured benzylsuccinate moiety.
• Peptidomimetics Research: Serves as a constrained scaffold or side-chain component in the design of peptide analogs and mimetics.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis or metal complexes.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(R)-(+)-2-Benzylsuccinic Acid 1-Methyl Ester
CAS No.	119807-84-0
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(R)-2-Benzylsuccinic Acid 1-Methyl Ester; (R)-(+)-Methyl 2-Benzylsuccinate; (R)-Methyl 2-Benzylbutanedioate; (2R)-2-Benzyl-4-methoxy-4-oxobutanoic Acid; (R)-1-Methoxy-1-oxo-3-phenylbutan-2-ylacetic Acid; (R)-2-Benzyl-4-methoxy-4-oxobutanoic Acid; (R)-2-(Phenylmethyl)butanedioic Acid 1-Methyl Ester
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-Benzylsuccinic Acid 1-Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral GC), identity confirmation (IR, NMR), and assay determination to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing specific results for purity, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.