Description

Carbamic Acid, (3-Amino-2-Hydroxy-1-Methylpropyl)-, 1,1-Dimethylethyl Ester is a specialized carbamate derivative that serves as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in providing a stable, tert-butyloxycarbonyl (Boc)-protected amine and hydroxyl functionality, enabling precise, multi-step synthetic routes. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for constructing complex molecules like active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those requiring protected amino alcohol motifs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide chemistry to introduce protected amino acid analogs.
• Chiral Auxiliary/Resolving Agent Precursor: Serves as a starting material for developing chiral auxiliaries due to its stereogenic centers.
• Protecting Group Chemistry: The Boc group provides orthogonal protection for amines in multi-functional molecule synthesis.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, targeted crop protection agents.

Basic Information

Product Name	Carbamic Acid, (3-Amino-2-Hydroxy-1-Methylpropyl)-, 1,1-Dimethylethyl Ester
CAS No.	119413-58-0
Molecular Formula	C9H20N2O3
Molecular Weight	204.27 g/mol
Synonyms	tert-Butyl (3-amino-2-hydroxy-1-methylpropyl)carbamate; (3-Amino-2-hydroxy-1-methylpropyl)carbamic acid tert-butyl ester; N-Boc-1,3-diamino-2-hydroxybutane; Boc-Dabinol; 1,1-Dimethylethyl N-(3-amino-2-hydroxy-1-methylpropyl)carbamate; 2-Hydroxy-1-methyl-3-[(tert-butoxycarbonyl)amino]propylamine; (R/S)-tert-Butyl (3-amino-2-hydroxy-1-methylpropyl)carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (3-Amino-2-Hydroxy-1-Methylpropyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.