Description

n-(Diphenylmethylene)-Glycine 1-Methylethyl Ester is a versatile and high-value protected amino acid derivative, specifically an imine-protected glycine isopropyl ester. This compound is a critical chiral building block and intermediate in advanced organic synthesis, prized for its role in constructing complex molecular architectures. It is essential for research and production in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs), peptides, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected glycine derivative for the solid-phase and solution-phase synthesis of peptides and peptidomimetics.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the glycine moiety while controlling chirality in target molecules.
• Agrochemical Research: An intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the research and development of specialty polymers and advanced organic materials.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	n-(Diphenylmethylene)-Glycine 1-Methylethyl Ester
CAS No.	119244-11-0
Molecular Formula	C18H19NO2
Molecular Weight	281.35 g/mol
Synonyms	Isopropyl 2-[(diphenylmethylene)amino]acetate; Glycine, N-(diphenylmethylene)-, 1-methylethyl ester; Diphenylmethylene Glycine Isopropyl Ester; Isopropyl N-(Diphenylmethylene)glycinate; N-(Diphenylmethylidene)glycine Isopropyl Ester; (Diphenylmethyleneamino)acetic Acid Isopropyl Ester; N-Benzhydrylideneglycine Isopropyl Ester
EINECS	Contact for details

Quality Control

Our n-(Diphenylmethylene)-Glycine 1-Methylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with cGMP, ISO, and REACH regulations as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.