Description

6-Chloro-7-Hydroxy-4-(Trifluoromethyl)Coumarin is a specialized fluorinated coumarin derivative that serves as a critical advanced intermediate and functional building block. Its unique structure, combining a coumarin core with chloro, hydroxy, and trifluoromethyl substituents, provides valuable photophysical and chemical properties for high-end applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes where the coumarin scaffold is active.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Fluorescent Probe & Sensor Development: Serves as a precursor for creating sensitive fluorescent dyes and chemosensors used in biochemical assays and diagnostic applications.
• Organic Light-Emitting Diode (OLED) Materials: Acts as an intermediate in the synthesis of electron-transport or emissive layer materials for display and lighting technologies.
• Polymer & Material Science: Incorporated into polymers to impart specific optical properties or as a monomer for advanced functional materials.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and other mechanistic studies due to its reactive hydroxy and chloro groups.

Basic Information

Product Name	6-Chloro-7-Hydroxy-4-(Trifluoromethyl)Coumarin
CAS No.	119179-66-7
Molecular Formula	C₁₀H₄ClF₃O₃
Molecular Weight	264.59 g/mol
Synonyms	6-Chloro-7-hydroxy-4-(trifluoromethyl)-2H-chromen-2-one; 4-(Trifluoromethyl)-6-chloro-7-hydroxycoumarin; 6-Chloro-7-hydroxy-4-trifluoromethylcoumarin; 2H-1-Benzopyran-2-one, 6-chloro-7-hydroxy-4-(trifluoromethyl)-; 6-Chloro-7-hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for identity confirmation and purity verification. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.