Description

3-Pentynoyl-S-Pantetheine-11-Pivalate is a specialized biochemical intermediate of significant interest in advanced pharmaceutical research and synthesis. This compound is valued for its role as a key building block in the development of novel enzyme inhibitors and targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic pathway studies, antibiotic development, and the synthesis of complex coenzyme A analogs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antibiotic compounds and enzyme inhibitors targeting bacterial fatty acid synthesis.
• Biochemical Research: Used as a tool compound in studying coenzyme A (CoA) biosynthesis pathways and pantothenate metabolism.
• Proteomics & Labeling Reagents: Serves as a functionalized handle for bioconjugation and affinity labeling studies due to its reactive alkyne moiety.
• Enzyme Substrate Analog: Employed in mechanistic studies of acyl carrier proteins (ACPs) and polyketide synthases (PKS).
• Precursor for CoA Analogs: Used in the chemical and enzymatic preparation of non-hydrolyzable or modified coenzyme A derivatives for therapeutic screening.

Basic Information

Product Name	3-Pentynoyl-S-Pantetheine-11-Pivalate
CAS No.	119072-37-6
Molecular Formula	C23H38N2O7S
Molecular Weight	486.63 g/mol
Synonyms	3-Pentynoyl-pantetheine pivalate; S-[2-(3-Pentynoylamino)ethyl] 11-[(2,2-dimethyl-1-oxopropoxy)amino]-4,9-dioxo-3,8,12-triazadodecan-6-thioate; Pantetheine-11-pivalate, 3-pentynoyl-; N-(3-Pentynoyl)-S-pantetheine-11-pivalate; Coenzyme A precursor analog; Pantothenate derivative
EINECS	Contact for details

Quality Control

Our 3-Pentynoyl-S-Pantetheine-11-Pivalate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.