Description

(1R,2R)-Ethyl 2-Hydroxycyclohexanecarboxylate is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry makes it a critical precursor for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chiral centers into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring the cis-1,2-cyclohexanediol motif.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to construct complex, stereodefined molecules.
• Agrochemical Development: Used in the research and production of chiral herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: A precursor for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is paramount.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(1R,2R)-Ethyl 2-Hydroxycyclohexanecarboxylate
CAS No.	119068-36-9
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	Ethyl (1R,2R)-2-hydroxycyclohexanecarboxylate; (1R,2R)-2-Hydroxycyclohexanecarboxylic Acid Ethyl Ester; cis-Ethyl 2-hydroxycyclohexanecarboxylate; (-)-Ethyl trans-2-hydroxycyclohexanecarboxylate; Ethyl (1R,2R)-(-)-2-hydroxycyclohexanecarboxylate; trans-Ethyl 2-hydroxycyclohexanecarboxylate (optical isomer); Cyclohexanecarboxylic acid, 2-hydroxy-, ethyl ester, (1R,2R)-
EINECS	Contact for details

Quality Control

Our (1R,2R)-Ethyl 2-Hydroxycyclohexanecarboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), enantiomeric excess (Chiral HPLC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.