Description

tert-Butyl 4,4,4-Trichlorobutanoate is a specialized organic ester building block of significant interest in advanced chemical synthesis. Its value lies in the reactive trichloromethyl group and the acid-labile tert-butyl ester moiety, making it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of novel drug candidates, particularly those requiring the incorporation of a trichloromethyl or carboxylic acid functionality.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trichloro group can impart specific biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules, leveraging the tert-butyl ester as a protecting group for carboxylic acids.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialty polymers with unique properties.
• Chemical Process Development: Utilized by process chemists to optimize scalable and efficient synthetic routes for target molecules in pilot plants and manufacturing.

Basic Information

Product Name	tert-Butyl 4,4,4-Trichlorobutanoate
CAS No.	119060-48-9
Molecular Formula	C8H13Cl3O2
Molecular Weight	247.54 g/mol
Synonyms	4,4,4-Trichlorobutanoic Acid tert-Butyl Ester; Butanoic Acid, 4,4,4-Trichloro-, 1,1-Dimethylethyl Ester; tert-Butyl 4,4,4-Trichlorobutyrate; 1,1-Dimethylethyl 4,4,4-Trichlorobutanoate; TBTCB; t-Butyl Trichlorobutanoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4,4,4-Trichlorobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.