Description

D-Alanine, n-Methyl-, Ethyl Ester (9Ci) is a high-purity, non-proteinogenic amino acid derivative with a specific stereochemistry and functionalization. This compound is a crucial chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise structural control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and specialized fine chemicals. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs and enzyme inhibitors.
• Peptidomimetics Research: Used to introduce modified alanine residues into peptide chains to enhance metabolic stability, bioavailability, and receptor binding affinity.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged amino acid analogs to study enzyme mechanisms and protein interactions.
• Agrochemical Synthesis: An intermediate in the development of chiral herbicides, fungicides, and plant growth regulators.
• Catalyst Ligand Preparation: Employed in the synthesis of chiral ligands for asymmetric catalysis in fine chemical manufacturing.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	D-Alanine, n-Methyl-, Ethyl Ester (9Ci)
CAS No.	118895-34-4
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	Ethyl (2R)-2-(Methylamino)propanoate; D-N-Methylalanine ethyl ester; (R)-2-(Methylamino)propionic acid ethyl ester; Ethyl D-2-(methylamino)propionate; D-α-(Methylamino)propionic Acid Ethyl Ester; (R)-Ethyl 2-(methylamino)propanoate; Alanine, N-methyl-, ethyl ester, D- (9CI)
EINECS	Contact for details

Quality Control

Our D-Alanine, n-Methyl-, Ethyl Ester (9Ci) is manufactured under a quality management system. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and specific impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong bases and should be kept away from incompatible materials. For long-term storage, consider keeping the container under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.