Description

Boc-Pyrrolidin-2-Yl-Acetic Acid Ethyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceuticals and bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetic design, medicinal chemistry, and the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting neurological disorders and metabolic diseases.
• Peptidomimetics Synthesis: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides, enhancing metabolic stability.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Protease Inhibitor Development: Serves as a core structure for designing inhibitors of specific enzymes like DPP-4 or prolyl oligopeptidase.
• Chemical Biology Probes: Utilized in the creation of labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	Boc-Pyrrolidin-2-Yl-Acetic Acid Ethyl Ester
CAS No.	118758-56-8
Molecular Formula	C13H23NO4
Molecular Weight	257.33 g/mol
Synonyms	Ethyl 2-[(tert-Butoxycarbonyl)amino]-2-pyrrolidineacetate; 2-[(tert-Butoxycarbonyl)amino]-2-pyrrolidineacetic Acid Ethyl Ester; N-Boc-2-Pyrrolidineglycine Ethyl Ester; N-(tert-Butoxycarbonyl)-2-pyrrolidineglycine Ethyl Ester; Boc-Pyrrolidin-2-yl-Gly-OEt; Boc-Pyrrolidine-2-yl-acetic acid ethyl ester; (2S)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-2-pyrrolidin-2-ylacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Boc-Pyrrolidin-2-Yl-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.