Description

1,2,3,4-Tetra-o-Acetyl-6-Deoxy-6-Fluoro-α-D-Galactopyranose is a key fluorinated carbohydrate derivative used as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound is specifically engineered to introduce a fluorine atom at the C-6 position of a galactose scaffold, enabling the study of metabolic pathways and the creation of novel bioactive molecules. It is essential for medicinal chemists and researchers in the pharmaceutical and biotechnology sectors working on glycosidase inhibitors, antiviral agents, and diagnostic probes.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of fluorinated nucleosides, antiviral drugs, and other therapeutic agents.
• Glycobiology Research: Used to study enzyme-substrate interactions, particularly with glycosidases and glycosyltransferases, by acting as a mechanism-based inhibitor or probe.
• Diagnostic Agent Development: Serves as a precursor for Positron Emission Tomography (PET) tracers, especially those labeled with fluorine-18 (18F).
• Chemical Biology Tool: Employed in the synthesis of fluorinated glycoconjugates and glycomimetics to investigate cell-surface interactions and signaling.
• Process Chemistry: Utilized in route scouting and scale-up for the commercial production of fluorinated active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-6-Deoxy-6-Fluoro-α-D-Galactopyranose
CAS No.	118396-36-4
Molecular Formula	C14H19FO9
Molecular Weight	350.29 g/mol
Synonyms	6-Deoxy-6-fluoro-α-D-galactopyranose 1,2,3,4-tetraacetate; 6-Fluoro-α-D-galactose tetraacetate; 1,2,3,4-Tetra-O-acetyl-6-deoxy-6-fluoro-α-D-galactopyranose; 6-Fluoro-α-D-galactopyranosyl tetraacetate; Tetra-O-acetyl-6-fluoro-α-D-galactopyranose; 6-Fluoro-1,2,3,4-tetra-O-acetyl-α-D-galactopyranose; α-D-6-Fluorogalactose tetraacetate
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-6-Deoxy-6-Fluoro-α-D-Galactopyranose is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Production adheres to cGMP guidelines where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We provide custom synthesis and purification services to meet specific project requirements, including chiral purity and defined impurity limits.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation [α]D20	+95° to +105° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.