Description

2-Phenylethynylpyridine-3-Carbonitrile is a specialized heterocyclic building block featuring a pyridine core functionalized with both a nitrile and a phenylethynyl group. This unique molecular architecture makes it a valuable intermediate for the synthesis of complex organic molecules, particularly in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and organic electronics industries for constructing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or precursor for conjugated polymers and organic semiconductors used in OLEDs and photovoltaic devices.
• Ligand Synthesis: Useful for creating novel ligands in coordination chemistry and catalysis.
• Fluorescent Probe Development: The conjugated system is exploited in the design of fluorescent dyes and molecular sensors.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry and synthetic methodology research in both university and corporate laboratories.

Basic Information

Product Name	2-Phenylethynylpyridine-3-Carbonitrile
CAS No.	118159-94-7
Molecular Formula	C14H8N2
Molecular Weight	204.23 g/mol
Synonyms	3-Cyano-2-(phenylethynyl)pyridine; 2-(Phenylethynyl)nicotinonitrile; 2-(2-Phenylethynyl)-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 2-(2-phenylethynyl)-; 2-(Phenylethynyl)-3-cyanopyridine; 2-(Phenylethynyl)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Phenylethynylpyridine-3-Carbonitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.