Description

2,3-Di-o-Acetyl-4,6-o-Ethylidene-Ss-D-Glucopyranose is a high-purity, protected carbohydrate derivative serving as a critical chiral building block and synthetic intermediate. This compound is essential for researchers and manufacturers requiring precise stereochemistry and functional group manipulation in complex organic syntheses. It is primarily utilized in the pharmaceutical industry for the development of novel active pharmaceutical ingredients (APIs), nucleoside analogs, and advanced glycoconjugates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Glycochemistry Research: Used in the study and synthesis of complex oligosaccharides, glycopeptides, and glycomimetics.
• Process Chemistry: Employed in the scalable production of specialty fine chemicals where protected sugar moieties are required.
• Bioconjugation: Acts as a precursor for linkers and spacers in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Catalyst and Ligand Synthesis: Useful for preparing chiral ligands and organocatalysts used in asymmetric synthesis.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2,3-Di-o-Acetyl-4,6-o-Ethylidene-Ss-D-Glucopyranose
CAS No.	118139-63-2
Molecular Formula	C₁₂H₁₈O₈
Molecular Weight	290.26 g/mol
Synonyms	4,6-O-Ethylidene-2,3-di-O-acetyl-α-D-glucopyranose; 2,3-Di-O-acetyl-4,6-O-ethylidene-D-glucopyranose; 4,6-O-Ethylidene-D-glucose diacetate; Ethylidene-protected glucose diacetate; α-D-Glucopyranose, 4,6-O-ethylidene-, 2,3-diacetate; 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose derivative (related intermediate); Protected D-glucose derivative
EINECS	Contact for details

Quality Control

Our 2,3-Di-o-Acetyl-4,6-o-Ethylidene-Ss-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.