Description

3-Methoxy-4-Trimethylsilylpyridine is a versatile organosilicon-protected pyridine derivative, serving as a key building block in advanced organic synthesis. Its value lies in the trimethylsilyl group, which acts as a protective and directing moiety, enabling selective functionalization at the pyridine core. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and complex heterocyclic molecules. Its unique structure facilitates challenging coupling reactions and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides due to its heterocyclic framework.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Derivatization: Used to introduce the methoxy and silyl functionalities into complex molecular architectures for property modulation.

Basic Information

Product Name	3-Methoxy-4-Trimethylsilylpyridine
CAS No.	118005-98-4
Molecular Formula	C9H15NOSi
Molecular Weight	181.31 g/mol
Synonyms	4-(Trimethylsilyl)-3-methoxypyridine; 3-Methoxy-4-(trimethylsilyl)pyridine; Pyridine, 3-methoxy-4-(trimethylsilyl)-; 3-Methoxypyridine-4-trimethylsilane
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-Trimethylsilylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial-scale synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.