Description

(E)-n-<1-(3-Pyridyl)Ethylidene>-4H-1,2,4-Triazol-4-Amine CAS NO 117979-29-0 is a specialized heterocyclic organic compound featuring a triazole core linked to a pyridyl moiety via an ethylidene bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis organizations for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with specific biological activity.
• Ligand Synthesis: Used in coordination chemistry to create complex ligands for catalysis or metal-organic frameworks (MOFs).
• Bioconjugation: The reactive amine and heterocyclic groups enable its use in linking molecules for diagnostic or therapeutic applications.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or electronic properties.
• Academic & Industrial R&D: A crucial building block for exploring structure-activity relationships (SAR) in medicinal and synthetic chemistry.

Basic Information

Product Name	(E)-n-<1-(3-Pyridyl)Ethylidene>-4H-1,2,4-Triazol-4-Amine
CAS No.	117979-29-0
Molecular Formula	C9H9N5
Molecular Weight	187.21 g/mol
Synonyms	(E)-N-[1-(3-Pyridinyl)ethylidene]-4H-1,2,4-triazol-4-amine; (E)-N-(1-(Pyridin-3-yl)ethylidene)-1H-1,2,4-triazol-4-amine; (E)-N'-(1-(3-Pyridyl)ethylidene)-4-amino-1,2,4-triazole; (E)-1-(3-Pyridyl)ethylideneamino-1,2,4-triazole; (E)-4-Amino-1,2,4-triazole N-(1-(3-pyridyl)ethylidene) derivative; 117979-29-0; Triazole-pyridine derivative
EINECS	Contact for details

Quality Control

Our production of (E)-n-<1-(3-Pyridyl)Ethylidene>-4H-1,2,4-Triazol-4-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we welcome client audits and specific testing requests.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.