Description

Dihydro-4,4-Dimethyl-3-(Phenylmethoxy)-2(3H)-Furanone is a specialized lactone derivative with a benzyl-protected hydroxyl group, serving as a valuable chiral building block and synthetic intermediate. Its molecular structure is engineered to provide precise stereochemical control and reactivity in complex organic syntheses. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, where it is utilized in the synthesis of active pharmaceutical ingredients (APIs) and other high-value target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a building block for constructing stereodefined centers in natural product synthesis and medicinal chemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific lactone motifs.
• Academic & Industrial Research: Serves as a reagent in methodological development and catalysis studies for organic transformations.
• Process Chemistry: Investigated for scalable routes in pilot plants and commercial manufacturing of advanced intermediates.

Basic Information

Product Name	Dihydro-4,4-Dimethyl-3-(Phenylmethoxy)-2(3H)-Furanone
CAS No.	117895-47-3
Molecular Formula	C13H16O3
Molecular Weight	220.27 g/mol
Synonyms	3-(Benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one; 4,4-Dimethyl-3-(phenylmethoxy)dihydro-2(3H)-furanone; 3-Benzyloxy-4,4-dimethylbutyrolactone; Dihydro-4,4-dimethyl-3-(benzyloxy)-2(3H)-furanone; 3-O-Benzyl-4,4-dimethylbutyrolactone; (3R)- or (3S)- isomers may be specified; Benzyl 4,4-dimethyl-3-hydroxybutyrate lactone ether
EINECS	Contact for details

Quality Control

Our Dihydro-4,4-Dimethyl-3-(Phenylmethoxy)-2(3H)-Furanone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for synthetic applications. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming identity, purity, and specified impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Chiral Purity (Chiral HPLC)	Specify enantiomer/excess upon request
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.