Description

(R)-Spiro[1,3-Dioxolane-2,1'(2'H)-Naphthalen]-6'(5'H)-One, 3',7',8',8'A-Tetrahydro-8'A-Methyl- (9Ci) is a high-purity chiral spirocyclic compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and complex molecular architecture make it invaluable for constructing sophisticated, three-dimensional frameworks. This product is essential for research and development chemists in the pharmaceutical and agrochemical sectors, particularly for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new asymmetric catalytic systems.
• Material Science: Potential monomer or precursor for creating specialized polymers with unique optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in total synthesis and the exploration of new spirocyclic chemistry.

Basic Information

Product Name	(R)-Spiro[1,3-Dioxolane-2,1'(2'H)-Naphthalen]-6'(5'H)-One, 3',7',8',8'A-Tetrahydro-8'A-Methyl- (9Ci)
CAS No.	117556-90-8
Molecular Formula	C₁₃H₁₄O₃
Molecular Weight	218.25 g/mol
Synonyms	(R)-8a-Methyl-3,4,8,8a-tetrahydro-1H-spiro[naphthalene-2,2'-[1,3]dioxolan]-6(5H)-one; (6'R)-8'a-Methyl-3',4',8',8'a-tetrahydro-1'H-spiro[[1,3]dioxolane-2,2'-naphthalen]-6'(5'H)-one; (R)-Spiro[dioxolane-naphthalenone]; (R)-8a-Methyl-3,4,8,8a-tetrahydrospiro[naphthalene-2,2'-[1,3]dioxolane]-6(5H)-one; (R)-Spirocyclic Dioxolane Naphthalenone; Chiral Spiro Dioxolane Ketone
EINECS	Contact for details

Quality Control

Our (R)-Spiro[1,3-Dioxolane-2,1'(2'H)-Naphthalen]-6'(5'H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.