Description

6-Ethoxy-4-(Trifluoromethyl)Pyridin-2-Amine is a high-value, multi-functional pyridine derivative characterized by its trifluoromethyl and ethoxy substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating novel ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry Building Block: The presence of the trifluoromethyl group makes it a valuable reagent for introducing fluorine atoms into complex molecules to modify their physicochemical properties.

Basic Information

Product Name	6-Ethoxy-4-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	117519-18-3
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	2-Amino-6-ethoxy-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-6-ethoxypyridin-2-amine; 6-Ethoxy-4-trifluoromethylpyridin-2-amine; 2-Pyridinamine, 6-ethoxy-4-(trifluoromethyl)-; 117519-18-3; 6-Ethoxy-4-(trifluoromethyl)-2-pyridinamine
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and MS analysis, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.