Description

2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and nitrated pyridine core. This compound matters for its versatility as a key intermediate in the synthesis of complex molecules, particularly in advanced agrochemicals and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, where the chloro and nitro groups serve as handles for further functionalization.
• Material Science Research: Employed in the development of specialty chemicals, liquid crystals, and functional polymers that require specific electronic properties.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.
• Nucleophilic Aromatic Substitution: The activated chlorine atom adjacent to the nitro group makes it an excellent electrophile for substitution reactions with various nucleophiles.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized dyes and pigments due to its nitro-aromatic structure.

Basic Information

Product Name	2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine
CAS No.	117519-08-1
Molecular Formula	C6H2ClF3N2O2
Molecular Weight	226.54 g/mol
Synonyms	2-Chloro-3-nitro-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-chloro-3-nitropyridine; 2-Chloro-3-nitro-α,α,α-trifluoro-p-toluidine (pyridine analog); Pyridine, 2-chloro-3-nitro-6-(trifluoromethyl)-; 3-Nitro-2-chloro-6-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.