Description

Methyl (E)-3-Methoxy-2-(2-Chloromethylphenyl)-2-Propenoate is a high-purity, synthetic organic intermediate characterized by its specific α,β-unsaturated ester structure with a chloromethylphenyl substituent. This compound is of significant commercial value for its role as a versatile building block in advanced chemical synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules via reactions such as Michael additions or further functional group transformations.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands or organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	Methyl (E)-3-Methoxy-2-(2-Chloromethylphenyl)-2-Propenoate
CAS No.	117428-51-0
Molecular Formula	C₁₂H₁₃ClO₃
Molecular Weight	240.68 g/mol
Synonyms	Methyl (E)-3-Methoxy-2-(2-(chloromethyl)phenyl)acrylate; Methyl 3-Methoxy-2-[(2-chloromethyl)phenyl]-2-propenoate; (E)-Methyl 3-methoxy-2-(2-(chloromethyl)phenyl)acrylate; 2-Propenoic acid, 3-methoxy-2-[2-(chloromethyl)phenyl]-, methyl ester, (E)-; Methyl α-Formylcinnamate derivative
EINECS	Contact for details

Quality Control

Our production of Methyl (E)-3-Methoxy-2-(2-Chloromethylphenyl)-2-Propenoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.