Description

Spiro[Bicyclo[3.1.0]Hex-3-Ene-2,2-[1,3]Dioxolane], 6-Methylene-, (-)- is a high-value, chiral spirocyclic compound featuring a unique bicyclo[3.1.0]hexene scaffold fused with a dioxolane ring. This specific stereoisomer is a critical advanced intermediate in the synthesis of complex pharmaceutical molecules and fine chemicals, prized for its rigid, three-dimensional structure which can impart desirable biological activity and selectivity. It is primarily sought after by research institutions and development chemists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where its complex structure can lead to compounds with unique modes of action.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry in chemical reactions.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or mechanical properties due to its strained ring system.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new cycloaddition reactions and methodologies for constructing spirocyclic compounds.

Basic Information

Product Name	Spiro[Bicyclo[3.1.0]Hex-3-Ene-2,2-[1,3]Dioxolane], 6-Methylene-, (-)-
CAS No.	117341-96-5
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(-)-6-Methylenespiro[bicyclo[3.1.0]hex-3-ene-2,2'-[1,3]dioxolane]; (1S,5R)-6-Methylidene-3-oxatricyclo[3.2.1.02,4]octan-4-one ethylene acetal; (-)-6-Methylenespiro[bicyclo[3.1.0]hex-3-ene-2,2'-1,3-dioxolane]; Spirocyclic dioxolane bicyclohexene derivative; Chiral spiro dioxolane.
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[3.1.0]Hex-3-Ene-2,2-[1,3]Dioxolane], 6-Methylene-, (-)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.