Description

4-tert-Butyldimethylsilyloxy-2-Diethylaminomethyl-2-Cyclopentene-1-One is a sophisticated, multi-functional organic intermediate featuring both silyl ether and aminoalkyl protecting groups on a cyclopentenone core. This compound matters because it serves as a critical building block in complex organic syntheses, enabling the controlled introduction of functional groups and facilitating challenging bond formations. Pharmaceutical and advanced agrochemical R&D laboratories need this high-purity intermediate for the development of novel active ingredients, particularly in the synthesis of prostaglandin analogs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of prostaglandin and prostacyclin analogs for cardiovascular and ophthalmic drug development.
• Agrochemical Synthesis: Building block for creating novel, high-performance active ingredients with specific biological activity.
• Organic Synthesis Reagent: Used in complex multi-step syntheses, particularly in reactions requiring selective protection/deprotection strategies.
• Medicinal Chemistry Research: Enables the exploration of new chemical entities (NCEs) and structure-activity relationships (SAR) in drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral template or intermediate in the production of enantiomerically pure compounds.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and novel reaction pathway exploration.

Basic Information

Product Name	4-tert-Butyldimethylsilyloxy-2-Diethylaminomethyl-2-Cyclopentene-1-One
CAS No.	117254-07-6
Molecular Formula	C16H31NO2Si
Molecular Weight	297.51 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]-2-[(diethylamino)methyl]-2-cyclopenten-1-one; 2-(Diethylaminomethyl)-4-(tert-butyldimethylsilyloxy)-2-cyclopenten-1-one; TBDMS-protected amino-cyclopentenone; 4-TBDMSO-2-diethylaminomethyl-2-cyclopenten-1-one; 4-(tert-Butyldimethylsiloxy)-2-(diethylaminomethyl)-2-cyclopenten-1-one; 2-Cyclopenten-1-one, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(diethylamino)methyl]-; CAS 117254-07-6
EINECS	Contact for details

Quality Control

Our 4-tert-Butyldimethylsilyloxy-2-Diethylaminomethyl-2-Cyclopentene-1-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support development projects requiring compliance with cGMP or other regulatory frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.