Description

Methyl 2-Hydroxy-2-(Trifluoromethyl)-4-Pentenoate is a high-value fluorinated building block and chiral intermediate essential for advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a reactive pentenoate moiety, makes it a critical precursor for creating complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of fluorinated drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers and coatings with specific surface properties.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and cross-coupling reactions to introduce fluorinated segments into complex molecular architectures.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands and organocatalysts for stereoselective transformations.

Basic Information

Product Name	Methyl 2-Hydroxy-2-(Trifluoromethyl)-4-Pentenoate
CAS No.	117015-45-9
Molecular Formula	C7H9F3O3
Molecular Weight	198.14 g/mol
Synonyms	2-Hydroxy-2-(trifluoromethyl)-4-pentenoic acid methyl ester; Methyl 2-hydroxy-2-(trifluoromethyl)pent-4-enoate; 4-Pentenoic acid, 2-hydroxy-2-(trifluoromethyl)-, methyl ester; 2-(Trifluoromethyl)-2-hydroxy-4-pentenoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Hydroxy-2-(Trifluoromethyl)-4-Pentenoate adheres to stringent quality management protocols. Each batch is analytically verified to meet precise purity and identity specifications, with testing typically including assay (HPLC), chiral purity, and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.