Description

5(6)-Cr 110 [5(6)-Carboxyrhodamine 110, Hydrochloride] is a high-purity, reactive derivative of the classic Rhodamine 110 fluorophore, widely recognized for its superior fluorescence quantum yield and photostability. This compound is essential for researchers and manufacturers requiring a reliable, bright, and versatile fluorescent labeling reagent for biomolecules. It is primarily used in the life sciences and diagnostics industries for applications such as nucleic acid sequencing, fluorescence microscopy, and flow cytometry.

Application

• Fluorescent Labeling of Biomolecules: Conjugation to oligonucleotides, peptides, and antibodies for detection and analysis.
• Nucleic Acid Sequencing & PCR: Used as a fluorescent tag in automated DNA sequencing (e.g., Sanger sequencing) and real-time PCR probes.
• Fluorescence Microscopy & Imaging: A key dye for cell staining, in situ hybridization (FISH), and live-cell imaging due to its brightness and photostability.
• Flow Cytometry & Diagnostics: Employed in the development of diagnostic assays and reagents for cell sorting and analysis.
• Biochemical Research: A fundamental tool for studying enzyme activity, protein interactions, and other dynamic biological processes.
• Sensor Development: Acts as a core fluorophore in the design of chemical and biological sensors for pH, ions, or specific analytes.

Basic Information

Product Name	5(6)-Cr 110 [5(6)-Carboxyrhodamine 110, Hydrochloride]
CAS No.	116763-35-0
Molecular Formula	C₂₆H₂₂ClN₂O₅
Molecular Weight	477.92 g/mol
Synonyms	5(6)-Carboxyrhodamine 110, Hydrochloride; 5(6)-CR 110; 5- and 6-Carboxyrhodamine 110 Mixed Isomers; Rhodamine 110 Carboxylic Acid; 6-Carboxy-2',4,5,7-tetramethylrhodamine; 6-TAMRA precursor; X-Rhodamine acid; 6-CR110; 5(6)-Carboxy-X-rhodamine
EINECS	Contact for details

Quality Control

Our 5(6)-Carboxyrhodamine 110, Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Single Isomer Content (HPLC)	≥ 45.0% (each, 5- and 6-isomer)
Water Content (KF)	≤ 5.0%
Fluorescence	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.