Description

Carbamic Acid, [(1R)-1-Formyl-2-(Methylthio)Ethyl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its role as a protected intermediate, enabling the controlled introduction of formyl and methylthio functional groups into complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly those exploring sulfur-containing or peptide-mimetic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates and proprietary molecules.
• Peptidomimetic Research: Used to incorporate modified amino acid structures into peptides to enhance stability, bioavailability, or biological activity.
• Asymmetric Synthesis: Serves as a starting material or intermediate in stereoselective reactions to construct complex chiral centers.
• Protecting Group Strategy: The tert-butyl ester group provides a stable protective moiety for the carbamate functionality during synthetic sequences.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this specialized intermediate.

Basic Information

Product Name	Carbamic Acid, [(1R)-1-Formyl-2-(Methylthio)Ethyl]-, 1,1-Dimethylethyl Ester
CAS No.	116754-91-7
Molecular Formula	C9H17NO3S
Molecular Weight	219.30 g/mol
Synonyms	N-[(1R)-1-Formyl-2-(methylthio)ethyl]carbamic acid tert-butyl ester; tert-Butyl N-[(1R)-1-formyl-2-(methylsulfanyl)ethyl]carbamate; (R)-2-((tert-Butoxycarbonyl)amino)-3-(methylthio)propanal; Boc-L-Methioninal; Boc-Met-aldehyde; (S)-2-((tert-Butoxycarbonyl)amino)-3-(methylthio)propanal (enantiomer); (1R)-1-Formyl-2-(methylthio)ethyl carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1R)-1-Formyl-2-(Methylthio)Ethyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid or colorless to pale yellow liquid/oil
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.