Description

D-Norvaline, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester is a protected amino acid derivative, specifically the methyl ester of Boc-D-norvaline, serving as a crucial chiral building block in organic synthesis. This compound matters for its role in constructing complex peptide structures and other bioactive molecules with high stereochemical fidelity. It is primarily needed by pharmaceutical R&D laboratories, peptide synthesis service providers, and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and complex organic molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of the D-norvaline residue.
• Proteomics Research: Employed in the design and synthesis of modified peptides for studying enzyme-substrate interactions and protein function.
• Chemical Biology: Serves as a building block for creating peptide mimetics, molecular probes, and other bioactive compounds.
• Agrochemical Development: Potential intermediate in the synthesis of chiral active ingredients for crop protection products.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and medicinal chemistry projects.

Basic Information

Product Name	D-Norvaline, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester
CAS No.	116611-58-6
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	Boc-D-norvaline methyl ester; (R)-2-((tert-Butoxycarbonyl)amino)pentanoic acid methyl ester; Methyl (R)-2-[(tert-butoxycarbonyl)amino]pentanoate; Methyl Boc-D-norvalinate; Boc-D-Nva-OMe; D-2-Amino-n-valeric acid, N-BOC-, methyl ester; Methyl N-Boc-D-norvalinate
EINECS	Contact for details

Quality Control

Our D-Norvaline, n-[(1,1-Dimethylethoxy)Carbonyl]-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.