Description

3-Acetyl-6-(Trifluoromethyl)-1,2-Dihydropyridin-2-One is a high-value, fluorinated heterocyclic building block with significant synthetic utility. Its core value lies in its unique molecular scaffold, which combines a reactive dihydropyridinone core with acetyl and trifluoromethyl substituents, enabling the construction of complex molecules for advanced research and development. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for use as a key intermediate in the synthesis of novel active ingredients, particularly those targeting enhanced bioavailability and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can impart improved lipophilicity and biological activity.
• Material Science Precursor: Serves as a specialized monomer or precursor for advanced polymers and functional materials with specific optical or electronic properties.
• Chemical Synthesis Reagent: Employed in organic synthesis for constructing complex heterocyclic frameworks via cyclization and functional group transformation reactions.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on understanding and applying fluorine chemistry in molecule design.

Basic Information

Item	Details
Product Name	3-Acetyl-6-(Trifluoromethyl)-1,2-Dihydropyridin-2-One
CAS No.	116548-05-1
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	3-Acetyl-6-(trifluoromethyl)-2(1H)-pyridinone; 6-(Trifluoromethyl)-3-acetyl-1,2-dihydropyridin-2-one; 3-Acetyl-6-trifluoromethyl-1H-pyridin-2-one; 2(1H)-Pyridinone, 3-acetyl-6-(trifluoromethyl)-; 3-Acetyl-6-trifluoromethyl-2-pyridone; 1,2-Dihydro-3-acetyl-6-(trifluoromethyl)-2-pyridinone
EINECS	Contact for details

Quality Control

Our 3-Acetyl-6-(Trifluoromethyl)-1,2-Dihydropyridin-2-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.