Description

2-Hydroxy-6-(Trifluoromethyl)Nicotinamide is a high-value trifluoromethyl-substituted pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, combining a nicotinamide core with hydroxy and trifluoromethyl substituents, makes it indispensable for creating novel compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzymes and receptors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental stability.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for heterocyclic chemistry and fluoroorganic compound synthesis.
• Material Science Precursor: Potential use in the development of specialty polymers, ligands for catalysis, or organic electronic materials due to its functionalized aromatic system.

Basic Information

Product Name	2-Hydroxy-6-(Trifluoromethyl)Nicotinamide
CAS No.	116548-03-9
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	6-(Trifluoromethyl)-2-pyridone-3-carboxamide; 2-Hydroxy-6-(trifluoromethyl)nicotinic acid amide; 2-Oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide; 3-Carbamoyl-6-(trifluoromethyl)-2-pyridone; 2-Hydroxy-6-trifluoromethylnicotinamide; 6-Trifluoromethyl-2-pyridone-3-carboxamide; 2-Pyridone-3-carboxamide, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-(Trifluoromethyl)Nicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.