Description

Methyl 6-Fluorochromone-2-Carboxylate is a high-purity fluorinated chromone derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in the strategic incorporation of fluorine, which can significantly alter the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas like oncology, CNS disorders, and inflammation.
• Agrochemical Research: Used in developing new-generation pesticides and herbicides, where the fluorochromone scaffold can contribute to enhanced efficacy and selectivity.
• Organic Synthesis: A versatile precursor for constructing complex heterocyclic compounds, including fused chromone and flavonoid analogs.
• Material Science: Potential intermediate for synthesizing organic electronic materials or fluorescent dyes due to the chromone core's photophysical properties.
• Chemical Biology: Useful as a probe or tag in biochemical research to study enzyme interactions or cellular processes.

Basic Information

Product Name	Methyl 6-Fluorochromone-2-Carboxylate
CAS No.	116543-91-0
Molecular Formula	C11H7FO4
Molecular Weight	222.17 g/mol
Synonyms	6-Fluorochromone-2-carboxylic acid methyl ester; Methyl 6-fluorochromone-2-carboxylate; 2-Methoxycarbonyl-6-fluorochromone; 6-Fluoro-2-carbomethoxychromone; 6-Fluoro-2-(methoxycarbonyl)chromone; Methyl 6-fluoro-2-chromonecarboxylate; 6-Fluoro-2-(methoxycarbonyl)-4H-chromen-4-one
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluorochromone-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets the agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.