Description

(2S,3R)-Methyl 3-((Methoxycarbonyl)Amino)-2-Methyl-3-Phenylpropanoate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a critical building block for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and development chemists and process engineers working in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and cardiovascular conditions.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct complex molecules with high enantiomeric excess.
• Peptidomimetics Research: Serves as a constrained amino acid derivative in the development of novel peptide-based therapeutics and enzyme inhibitors.
• Agrochemical Development: Employed in the research and production of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Catalyst Ligand Synthesis: A starting material for the preparation of chiral ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	(2S,3R)-Methyl 3-((Methoxycarbonyl)Amino)-2-Methyl-3-Phenylpropanoate
CAS No.	116507-58-5
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	Methyl (2S,3R)-3-[(Methoxycarbonyl)Amino]-2-Methyl-3-Phenylpropanoate; (2S,3R)-Methyl 3-(Methoxycarbonylamino)-2-methyl-3-phenylpropionate; L-threo-β-Methylphenylalanine N-Carbomethoxy Methyl Ester; Methyl N-[(1S,2R)-1-(Methoxycarbonyl)-2-methyl-3-phenylpropyl]carbamate; (2S,3R)-3-[(Methoxycarbonyl)amino]-2-methyl-3-phenylpropionic acid methyl ester; NSC 330836; A chiral β-amino acid derivative.
EINECS	Contact for details

Quality Control

Our (2S,3R)-Methyl 3-((Methoxycarbonyl)Amino)-2-Methyl-3-Phenylpropanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard identification tests, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.