Description

5-Fluoro-3-(1-Methyl-1,2,3,6-Tetrahydro-4-Pyridinyl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and neurological disorder treatments.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates targeting serotonin and dopamine receptors.
• Neurological Research: Used in the research and development of potential treatments for conditions such as depression, anxiety, and schizophrenia.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed as a reference standard or ligand in receptor binding assays and other pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.

Basic Information

Product Name	5-Fluoro-3-(1-Methyl-1,2,3,6-Tetrahydro-4-Pyridinyl)-1H-Indole
CAS No.	116480-54-7
Molecular Formula	C14H15FN2
Molecular Weight	230.28 g/mol
Synonyms	5-Fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 5-Fluoro-3-(1-methyl-4-piperidinyl)-1H-indole (tautomer); 5-Fluoro-3-(N-methyl-4-piperidinyl)indole; 116480-54-7; 5-Fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridyl)indole; 3-(1-Methyl-1,2,3,6-tetrahydro-4-pyridinyl)-5-fluoro-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(1-Methyl-1,2,3,6-Tetrahydro-4-Pyridinyl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.