Description

tert-Butyl 3-acetyl-4-oxopentanoate is a high-purity, versatile β-keto ester building block essential for advanced organic synthesis. Its value lies in its dual reactive carbonyl sites, enabling its use as a key precursor in the construction of complex heterocyclic and pharmaceutical intermediates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug molecules, particularly those containing pyridine, pyrrole, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators requiring specific β-keto ester motifs.
• Fine Chemical Building Block: Employed in multi-step organic synthesis for creating specialty chemicals, flavors, fragrances, and functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on Claisen condensations and Michael addition reactions.
• Coordination Chemistry: Can act as a ligand precursor or be used to synthesize chelating agents due to its carbonyl and ester functional groups.

Basic Information

Product Name	tert-Butyl 3-Acetyl-4-Oxopentanoate
CAS No.	116423-03-1
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	3-Acetyl-4-oxopentanoic acid tert-butyl ester; tert-Butyl 3-acetyl-4-oxovalerate; 4-Oxopentanoic acid, 3-acetyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-acetyl-4-oxopentanoate; 3-Acetyllevulinic acid tert-butyl ester; tert-Butyl acetoacetate acetate; β-Keto ester derivative; TB-3A4OP
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-acetyl-4-oxopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.