Description

Methyl-(6R)-((T-Butyl) Diphenylsilyloxy)-(2E,4E,8Z)-Tetradecatrienoate is a high-purity, stereochemically defined synthetic intermediate of significant value in advanced organic synthesis. This compound matters for its role as a key chiral building block in the production of complex bioactive molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, agrochemicals, and specialty fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of prostaglandin analogs and other bioactive lipid mediators.
• Agrochemical Research: Used in the development of advanced pesticides and plant growth regulators with specific stereochemical activity.
• Organic Synthesis: Serves as a versatile building block for constructing complex polyene chains and introducing protected hydroxyl functionalities in a stereocontrolled manner.
• Academic & R&D: Employed in methodological studies and total synthesis projects within university and industrial research laboratories.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value specialty chemicals and flavors/fragrances precursors.

Basic Information

Product Name	Methyl-(6R)-((T-Butyl) Diphenylsilyloxy)-(2E,4E,8Z)-Tetradecatrienoate
CAS No.	116279-81-3
Molecular Formula	C31H42O3Si
Molecular Weight	490.75 g/mol
Synonyms	Methyl (2E,4E,8Z)-6-[(tert-Butyldiphenylsilyl)oxy]tetradeca-2,4,8-trienoate; (6R)-6-[(tert-Butyldiphenylsilyl)oxy]methyl (2E,4E,8Z)-tetradecatrienoate; TBDPS-protected methyl tetradecatrienoate; Prostaglandin Intermediate; CAS 116279-81-3; tert-Butyldiphenylsilyl Ether of Methyl (6R)-Hydroxy-(2E,4E,8Z)-tetradecatrienoate
EINECS	Contact for details

Quality Control

Our Methyl-(6R)-((T-Butyl) Diphenylsilyloxy)-(2E,4E,8Z)-Tetradecatrienoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) with full specification data are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. The compound is sensitive to fluoride ions and strong alkali; ensure it is stored separately from such materials. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.