Description

(S)-Benzyl Piperidine-2-Carboxylate is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its well-defined stereochemistry, which is critical for developing enantiomerically pure pharmaceuticals and bioactive compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for asymmetric synthesis and API development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Peptidomimetics & Drug Discovery: Serves as a constrained amino acid analog in the design and synthesis of peptide-like molecules for medicinal chemistry programs.
• Agrochemical Research: Employed in the synthesis of chiral active ingredients for crop protection agents, where specific stereochemistry can influence biological activity.
• Catalyst & Ligand Preparation: Acts as a starting material for the synthesis of chiral ligands used in homogeneous catalysis.
• Academic & R&D Laboratories: A valuable compound for methodological studies in organic chemistry and for training purposes in advanced synthetic techniques.

Basic Information

Product Name	(S)-Benzyl Piperidine-2-Carboxylate
CAS No.	116261-43-9
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	(S)-(-)-Benzyl 2-Piperidinecarboxylate; (S)-Benzyl 2-Piperidinecarboxylate; (S)-1-Benzyloxycarbonyl-2-piperidinecarboxylic Acid (lactam form); (2S)-1-[(Benzyloxy)carbonyl]piperidine-2-carboxylic Acid; (S)-N-Cbz-Pipecolic Acid; (S)-N-Carbobenzyloxy-Pipecolic Acid; (S)-1-CBZ-Pipecolic Acid; (S)-Piperidine-2-carboxylic Acid Benzyl Ester
EINECS	Contact for details

Quality Control

Our (S)-Benzyl Piperidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.